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FITC-Labeled Alendronate as an In Vivo Bone pH Sensor

pH is a critical indicator of bone physiological function and disease status; however, noninvasive and real-time sensing of bone pH in vivo has been a challenge. Here, we synthesized a bone pH sensor by labeling alendronate with the H+-sensitive dye fluorescein isothiocyanate (Aln-FITC). Aln-FITC sh...

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Detalles Bibliográficos
Autores principales: Li, Yuzhou, Fu, Yiru, Zhang, He, Song, Jinlin, Yang, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256770/
https://www.ncbi.nlm.nih.gov/pubmed/32550231
http://dx.doi.org/10.1155/2020/4012194