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Improved Production of Recombinant Human β-NGF in Escherichia coli – a Bioreactor Scale Study
Human nerve growth factor β (β-NGF) is considered a major therapeutic agent for treatment of neurodegenerative diseases. We have previously reported the optimized conditions for β-NGF overproduction in Escherichia coli in a shake-flask culture. In this study the optimal %DO (dissolved oxygen) and po...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Exeley Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256796/ https://www.ncbi.nlm.nih.gov/pubmed/30451453 http://dx.doi.org/10.21307/pjm-2018-045 |