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Integrin-Mediated Adhesion and Chemoresistance of Acute Lymphoblastic Leukemia Cells Residing in the Bone Marrow or the Central Nervous System

Acute Lymphoblastic Leukemia (ALL) is the most common cancer in childhood. Despite a significantly improved prognosis over the last decade with a 5-years survival rate of ~90%, treatment-related morbidity remains substantial and relapse occurs in 10–15% of patients (1). The most common site of relap...

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Detalles Bibliográficos
Autores principales: Scharff, Bibi Fatima Syed Shah, Modvig, Signe, Marquart, Hanne Vibeke, Christensen, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256886/
https://www.ncbi.nlm.nih.gov/pubmed/32528884
http://dx.doi.org/10.3389/fonc.2020.00775