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Defining the Design Parameters for in Vivo Enzyme Delivery Through Protein Spherical Nucleic Acids
[Image: see text] The translation of proteins as effective intracellular drug candidates is limited by the challenge of cellular entry and their vulnerability to degradation. To advance their therapeutic potential, cell-impermeable proteins can be readily transformed into protein spherical nucleic a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256953/ https://www.ncbi.nlm.nih.gov/pubmed/32490197 http://dx.doi.org/10.1021/acscentsci.0c00313 |