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Functional production of human antibody by the filamentous fungus Aspergillus oryzae

BACKGROUND: Monoclonal antibodies (mAbs) as biopharmaceuticals take a pivotal role in the current therapeutic applications. Generally mammalian cell lines, such as those derived from Chinese hamster ovaries (CHO), are used to produce the recombinant antibody. However, there are still concerns about...

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Detalles Bibliográficos
Autores principales: Huynh, Hung Hiep, Morita, Naoki, Sakamoto, Toshihiro, Katayama, Takuya, Miyakawa, Takuya, Tanokura, Masaru, Chiba, Yasunori, Shinkura, Reiko, Maruyama, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257131/
https://www.ncbi.nlm.nih.gov/pubmed/32514366
http://dx.doi.org/10.1186/s40694-020-00098-w