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Functional production of human antibody by the filamentous fungus Aspergillus oryzae
BACKGROUND: Monoclonal antibodies (mAbs) as biopharmaceuticals take a pivotal role in the current therapeutic applications. Generally mammalian cell lines, such as those derived from Chinese hamster ovaries (CHO), are used to produce the recombinant antibody. However, there are still concerns about...
Autores principales: | Huynh, Hung Hiep, Morita, Naoki, Sakamoto, Toshihiro, Katayama, Takuya, Miyakawa, Takuya, Tanokura, Masaru, Chiba, Yasunori, Shinkura, Reiko, Maruyama, Jun-ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257131/ https://www.ncbi.nlm.nih.gov/pubmed/32514366 http://dx.doi.org/10.1186/s40694-020-00098-w |
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