Cargando…

Tbx2 mediates dorsal patterning and germ layer suppression through inhibition of BMP/GDF and Activin/Nodal signaling

BACKGROUND: Members of the T-box family of DNA-binding proteins play a prominent role in the differentiation of the three primary germ layers. VegT, Brachyury, and Eomesodermin function as transcriptional activators and, in addition to directly activating the transcription of endoderm- and mesoderm-...

Descripción completa

Detalles Bibliográficos
Autores principales: Reich, Shoshana, Kayastha, Peter, Teegala, Sushma, Weinstein, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257154/
https://www.ncbi.nlm.nih.gov/pubmed/32466750
http://dx.doi.org/10.1186/s12860-020-00282-1