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Novel role of PAF1 in attenuating radiosensitivity in cervical cancer by inhibiting IER5 transcription

BACKGROUND: Radiosensitivity is limited in cervical cancer (CC) patients due to acquired radiation resistance. In our previous studies, we found that immediate-early response 5 (IER5) is upregulated in CC cells upon radiation exposure and decreases cell survival by promoting apoptosis. The details o...

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Detalles Bibliográficos
Autores principales: Zheng, Jing-Jie, He, Yue, Liu, Yang, Li, Feng-Shuang, Cui, Zhen, Du, Xiao-Meng, Wang, Chun-Peng, Wu, Yu-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257241/
https://www.ncbi.nlm.nih.gov/pubmed/32471508
http://dx.doi.org/10.1186/s13014-020-01580-w