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TDAG8 deficiency reduces satellite glial number and pro-inflammatory macrophage number to relieve rheumatoid arthritis disease severity and chronic pain

BACKGROUND: The autoimmune disease rheumatoid arthritis (RA) affects approximately 1% of the global population. RA is characterized with chronic joint inflammation and often associated with chronic pain. The imbalance of pro-inflammatory and anti-inflammatory macrophages is a feature of RA progressi...

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Detalles Bibliográficos
Autores principales: Dai, Shih-Ping, Hsieh, Wei-Shan, Chen, Chien-Hua, Lu, Yueh-Hao, Huang, Hsu-Shan, Chang, Der-Ming, Huang, Shir-Ly, Sun, Wei-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257243/
https://www.ncbi.nlm.nih.gov/pubmed/32471455
http://dx.doi.org/10.1186/s12974-020-01851-z