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Fibroblast Growth Factor–21 ameliorates hepatic encephalopathy by activating the STAT3-SOCS3 pathway to inhibit activated hepatic stellate cells

Neurological dysfunction, one of the consequences of acute liver failure (ALF), and also referred to as hepatic encephalopathy (HE), contributes to mortality posing challenges for clinical management. FGF21 has been implicated in the inhibition of cognitive decline and fibrogenesis. However, the eff...

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Detalles Bibliográficos
Autores principales: Opoku, Yeboah Kwaku, Liu, Zhihang, Afrifa, Justice, Kumi, Asare Kwame, Liu, Han, Ghartey-Kwansah, George, Koranteng, Harriet, Jiang, Xinghao, Ren, Guiping, Li, Deshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257252/
https://www.ncbi.nlm.nih.gov/pubmed/32483404
http://dx.doi.org/10.17179/excli2020-1287