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No Adaptation of the Prion Strain in a Heterozygous Case of Variant Creutzfeldt-Jakob Disease

We investigated a clinical case of variant Creutzfeldt-Jakob Disease in a person heterozygous for methionine/valine at codon 129 of the prion protein gene and identified the same strain properties in variant Creutzfeldt-Jakob disease in methionine homozygous persons and in bovine spongiform encephal...

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Detalles Bibliográficos
Autores principales: Boyle, Aileen, Plinston, Chris, Laing, Fraser, Mackenzie, Graeme, Will, Robert G., Manson, Jean C., Diack, Abigail B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7258451/
https://www.ncbi.nlm.nih.gov/pubmed/32441626
http://dx.doi.org/10.3201/eid2606.191116