A TrkB agonist and ampakine rescue synaptic plasticity and multiple forms of memory in a mouse model of intellectual disability

Fragile X syndrome (FXS) is associated with deficits in various types of learning, including those that require the hippocampus. Relatedly, hippocampal long-term potentiation (LTP) is impaired in the Fmr1 knockout (KO) mouse model of FXS. Prior research found that infusion of brain-derived neurotrop...

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Detalles Bibliográficos
Autores principales: Seese, Ronald R., Le, Aliza A., Wang, Kathleen, Cox, Conor D., Lynch, Gary, Gall, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7258745/
https://www.ncbi.nlm.nih.gov/pubmed/31494285
http://dx.doi.org/10.1016/j.nbd.2019.104604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7258745/
https://www.ncbi.nlm.nih.gov/pubmed/31494285
http://dx.doi.org/10.1016/j.nbd.2019.104604

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