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Discovering small molecules as Wnt inhibitors that promote heart regeneration and injury repair

There are intense interests in discovering proregenerative medicine leads that can promote cardiac differentiation and regeneration, as well as repair damaged heart tissues. We have combined zebrafish embryo-based screens with cardiomyogenesis assays to discover selective small molecules that modula...

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Detalles Bibliográficos
Autores principales: Xie, Shuying, Fu, Wenbin, Yu, Guangju, Hu, Xueli, Lai, Kaa Seng, Peng, Xiangwen, Zhou, Yating, Zhu, Xuejiao, Christov, Plamen, Sawyer, Leah, Ni, Terri T, Sulikowski, Gary A, Yang, Zhongzhou, Lee, Ethan, Zeng, Chunyu, Wang, Wei E, Zhong, Tao P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259332/
https://www.ncbi.nlm.nih.gov/pubmed/30925593
http://dx.doi.org/10.1093/jmcb/mjz023