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Deficiency of PTEN and CDKN2A Tumor-Suppressor Genes in Conventional and Chondroid Chordomas: Molecular Characteristics and Clinical Relevance

INTRODUCTION: Chordoma is a malignant tumor predominantly involving the skull base and vertebral column. This study aimed to investigate the molecular characteristics of PTEN and CDKN2A in conventional and chondroid chordomas and their correlation with clinical prognosis. MATERIALS AND METHODS: A to...

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Detalles Bibliográficos
Autores principales: Yang, Chenlong, Sun, Jianjun, Yong, Lei, Liang, Chen, Liu, Tie, Xu, Yulun, Yang, Jun, Liu, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259488/
https://www.ncbi.nlm.nih.gov/pubmed/32547095
http://dx.doi.org/10.2147/OTT.S252990