Hypomethylation of IL1RN and NFKB1 genes is linked to the dysbalance in IL1β/IL-1Ra axis in female patients with type 2 diabetes mellitus

Inflammation has received considerable attention in the pathogenesis of type 2 diabetes mellitus (T2DM). Supporting this concept, enhanced expression of interleukin (IL)-1β and increased infiltration of macrophages are observed in pancreatic islets of patients with T2DM. Although IL-1 receptor antag...

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Detalles Bibliográficos
Autores principales: Margaryan, Sona, Kriegova, Eva, Fillerova, Regina, Smotkova Kraiczova, Veronika, Manukyan, Gayane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259508/
https://www.ncbi.nlm.nih.gov/pubmed/32470060
http://dx.doi.org/10.1371/journal.pone.0233737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259508/
https://www.ncbi.nlm.nih.gov/pubmed/32470060
http://dx.doi.org/10.1371/journal.pone.0233737

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