IL-12 from endogenous cDC1, and not vaccine DC, is required for Th1 induction

Success of DC vaccines relies on the quality of antigen presentation, costimulation, lymph node migration, and the release of IL-12, in case of Th1 priming. Here, we provide evidence for interaction between the injected vaccine DCs with endogenous lymph node–resident DCs for Th1 induction. While mig...

Descripción completa

Detalles Bibliográficos
Autores principales: Ashour, DiyaaElDin, Arampatzi, Panagiota, Pavlovic, Vladimir, Förstner, Konrad U., Kaisho, Tsuneyasu, Beilhack, Andreas, Erhard, Florian, Lutz, Manfred B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259537/
https://www.ncbi.nlm.nih.gov/pubmed/32434994
http://dx.doi.org/10.1172/jci.insight.135143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259537/
https://www.ncbi.nlm.nih.gov/pubmed/32434994
http://dx.doi.org/10.1172/jci.insight.135143

Ejemplares similares