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Amyloid β induces interneuron-specific changes in the hippocampus of APP(NL-F) mice
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by cognitive decline and amyloid-beta (Aβ) depositions generated by the proteolysis of amyloid precursor protein (APP) in the brain. In APP(NL-F) mice, APP gene was humanized and contains two familial AD mutations, and APP–unlike...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259556/ https://www.ncbi.nlm.nih.gov/pubmed/32469963 http://dx.doi.org/10.1371/journal.pone.0233700 |