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Heparin and non-anticoagulant heparin attenuate histone-induced inflammatory responses in whole blood
Cytotoxic and pro-inflammatory histones are present in neutrophil extracellular traps (NETs) and are elevated in blood in several inflammatory conditions, sepsis being a major example. Compounds which can attenuate activities of histones are therefore of interest, with heparin being one such materia...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259574/ https://www.ncbi.nlm.nih.gov/pubmed/32469940 http://dx.doi.org/10.1371/journal.pone.0233644 |