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Molecular interactions between monoclonal oligomer-specific antibody 5E3 and its amyloid beta cognates

Oligomeric amyloid β (Aβ) is currently considered the most neurotoxic form of the Aβ peptide implicated in Alzheimer’s disease (AD). The molecular structures of the oligomers have remained mostly unknown due to their transient nature. As a result, the molecular mechanisms of interactions between con...

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Detalles Bibliográficos
Autores principales: Khorvash, Massih, Blinov, Nick, Ladner-Keay, Carol, Lu, Jie, Silverman, Judith M., Gibbs, Ebrima, Wang, Yu Tian, Kovalenko, Andriy, Wishart, David, Cashman, Neil R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259632/
https://www.ncbi.nlm.nih.gov/pubmed/32469918
http://dx.doi.org/10.1371/journal.pone.0232266