Oral Immunization with HIV-1 Envelope SOSIP trimers elicits systemic immune responses and cross-reactive anti-V1V2 antibodies in non-human primates

Development of a successful HIV vaccine is dependent upon a determination of the optimum antigen and adjuvant as well as choosing an optimal site for vaccine delivery. The site of delivery is particularly relevant as HIV transmission generally requires that the virus crosses a mucosal membrane to in...

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Detalles Bibliográficos
Autores principales: Fisher, Bridget S., Dambrauskas, Nicholas, Trakhimets, Olesya, Andrade, Daniela V., Smedley, Jeremy, Sodora, Donald L., Sather, D. Noah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259690/
https://www.ncbi.nlm.nih.gov/pubmed/32470041
http://dx.doi.org/10.1371/journal.pone.0233577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259690/
https://www.ncbi.nlm.nih.gov/pubmed/32470041
http://dx.doi.org/10.1371/journal.pone.0233577

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