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Effects of Biotin on survival, ensheathment, and ATP production by oligodendrocyte lineage cells in vitro

Mechanisms implicated in disease progression in multiple sclerosis include continued oligodendrocyte (OL)/myelin injury and failure of myelin repair. Underlying causes include metabolic stress with resultant energy deficiency. Biotin is a cofactor for carboxylases involved in ATP production that imp...

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Detalles Bibliográficos
Autores principales: Cui, Qiao-Ling, Lin, Yun Hsuan, Xu, Yu Kang T., Fernandes, Milton G. F., Rao, Vijayaraghava T. S., Kennedy, Timothy E., Antel, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259710/
https://www.ncbi.nlm.nih.gov/pubmed/32470040
http://dx.doi.org/10.1371/journal.pone.0233859