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Determination of piperaquine concentration in human plasma and the correlation of capillary versus venous plasma concentrations

BACKGROUND: A considerable challenge in quantification of the antimalarial piperaquine in plasma is carryover of analyte signal between assays. Current intensive pharmacokinetic studies often rely on the merging of venous and capillary sampling. Drug levels in capillary plasma may be different from...

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Detalles Bibliográficos
Autores principales: Mwebaza, Norah, Cheah, Vincent, Forsman, Camilla, Kajubi, Richard, Marzan, Florence, Wallender, Erika, Dorsey, Grant, Rosenthal, Philip J., Aweeka, Francesca, Huang, Liusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259774/
https://www.ncbi.nlm.nih.gov/pubmed/32470030
http://dx.doi.org/10.1371/journal.pone.0233893