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Iatrogenic Cushing syndrome and multifocal osteonecrosis caused by the interaction between inhaled fluticasone and ritonavir

Inhaled corticosteroids are generally considered safe and do not usually lead to systemic adverse events since their plasma concentrations are low due to hepatic metabolism by the cytochrome P450 3A4. However, when associated with inhibitors of this cytochrome, such as ritonavir, they may lead to ia...

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Detalles Bibliográficos
Autores principales: Figueiredo, Joana, Serrado, Margarida, Khmelinskii, Nikita, do Vale, Sónia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259854/
https://www.ncbi.nlm.nih.gov/pubmed/32467117
http://dx.doi.org/10.1136/bcr-2019-233712