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Canonical signaling by TGF family members in mesenchymal stromal cells is dispensable for hematopoietic niche maintenance under basal and stress conditions

Mesenchymal stromal cells are an important component of the bone marrow hematopoietic niche. Prior studies showed that signaling from members of the transforming growth factor (TGF) superfamily in mesenchymal stromal cells is required for normal niche development. Here, we assessed the impact of TGF...

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Detalles Bibliográficos
Autores principales: Krambs, Joseph Ryan, Abou Ezzi, Grazia, Yao, Juo-Chin, Link, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259882/
https://www.ncbi.nlm.nih.gov/pubmed/32470079
http://dx.doi.org/10.1371/journal.pone.0233751