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Generation of self-organized sensory ganglion organoids and retinal ganglion cells from fibroblasts

Neural organoids provide a powerful tool for investigating neural development, modeling neural diseases, screening drugs, and developing cell-based therapies. Somatic cells have previously been reprogrammed by transcription factors (TFs) into sensory ganglion (SG) neurons but not SG organoids. We id...

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Detalles Bibliográficos
Autores principales: Xiao, Dongchang, Deng, Qinqin, Guo, Yanan, Huang, Xiuting, Zou, Min, Zhong, Jiawei, Rao, Pinhong, Xu, Zihui, Liu, Yifan, Hu, Youjin, Shen, Yin, Jin, Kangxin, Xiang, Mengqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259937/
https://www.ncbi.nlm.nih.gov/pubmed/32523990
http://dx.doi.org/10.1126/sciadv.aaz5858