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Generation of self-organized sensory ganglion organoids and retinal ganglion cells from fibroblasts
Neural organoids provide a powerful tool for investigating neural development, modeling neural diseases, screening drugs, and developing cell-based therapies. Somatic cells have previously been reprogrammed by transcription factors (TFs) into sensory ganglion (SG) neurons but not SG organoids. We id...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259937/ https://www.ncbi.nlm.nih.gov/pubmed/32523990 http://dx.doi.org/10.1126/sciadv.aaz5858 |