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Single-molecule transport kinetics of a glutamate transporter homolog shows static disorder

Kinetic properties of membrane transporters are typically poorly defined because high-resolution functional assays analogous to single-channel recordings are lacking. Here, we measure single-molecule transport kinetics of a glutamate transporter homolog from Pyrococcus horikoshii, Glt(Ph), using flu...

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Detalles Bibliográficos
Autores principales: Ciftci, Didar, Huysmans, Gerard H. M., Wang, Xiaoyu, He, Changhao, Terry, Daniel, Zhou, Zhou, Fitzgerald, Gabriel, Blanchard, Scott C., Boudker, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259943/
https://www.ncbi.nlm.nih.gov/pubmed/32523985
http://dx.doi.org/10.1126/sciadv.aaz1949