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Mfsd2a and Spns2 are essential for sphingosine-1-phosphate transport in the formation and maintenance of the blood-brain barrier

To maintain brain homeostasis, a unique interface known as the blood-brain barrier (BBB) is formed between the blood circulation and the central nervous system (CNS). Major facilitator superfamily domain-containing 2a (Mfsd2a) is a specific marker of the BBB. However, the mechanism by which Mfsd2a i...

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Detalles Bibliográficos
Autores principales: Wang, Zhifu, Zheng, Yongtao, Wang, Fan, Zhong, Junjie, Zhao, Tong, Xie, Qiang, Zhu, Tongming, Ma, Fukai, Tang, Qisheng, Zhou, Bin, Zhu, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259944/
https://www.ncbi.nlm.nih.gov/pubmed/32523984
http://dx.doi.org/10.1126/sciadv.aay8627