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Maternal spindle transfer overcomes embryo developmental arrest caused by ooplasmic defects in mice

The developmental potential of early embryos is mainly dictated by the quality of the oocyte. Here, we explore the utility of the maternal spindle transfer (MST) technique as a reproductive approach to enhance oocyte developmental competence. Our proof-of-concept experiments show that replacement of...

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Detalles Bibliográficos
Autores principales: Costa-Borges, Nuno, Spath, Katharina, Miguel-Escalada, Irene, Mestres, Enric, Balmaseda, Rosa, Serafín, Anna, Garcia-Jiménez, Maria, Vanrell, Ivette, González, Jesús, Rink, Klaus, Wells, Dagan, Calderón, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259950/
https://www.ncbi.nlm.nih.gov/pubmed/32347793
http://dx.doi.org/10.7554/eLife.48591