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Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates

The body plan along the anteroposterior axis and regional identities are specified by the spatiotemporal expression of Hox genes. Multistep controls are required for their unique expression patterns; however, the molecular mechanisms behind the tight control of Hox genes are not fully understood. In...

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Detalles Bibliográficos
Autores principales: Sato, Tempei, Kataoka, Kensuke, Ito, Yoshiaki, Yokoyama, Shigetoshi, Inui, Masafumi, Mori, Masaki, Takahashi, Satoru, Akita, Keiichi, Takada, Shuji, Ueno-Kudoh, Hiroe, Asahara, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259951/
https://www.ncbi.nlm.nih.gov/pubmed/32479258
http://dx.doi.org/10.7554/eLife.53608