Mesenchymal niche remodeling impairs hematopoiesis via stanniocalcin 1 in acute myeloid leukemia

Acute myeloid leukemia (AML) disrupts the generation of normal blood cells, predisposing patients to hemorrhage, anemia, and infections. Differentiation and proliferation of residual normal hematopoietic stem and progenitor cells (HSPCs) are impeded in AML-infiltrated bone marrow (BM). The underlyin...

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Detalles Bibliográficos
Autores principales: Waclawiczek, Alexander, Hamilton, Ashley, Rouault-Pierre, Kevin, Abarrategi, Ander, Albornoz, Manuel Garcia, Miraki-Moud, Farideh, Bah, Nourdine, Gribben, John, Fitzgibbon, Jude, Taussig, David, Bonnet, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260026/
https://www.ncbi.nlm.nih.gov/pubmed/32364536
http://dx.doi.org/10.1172/JCI133187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260026/
https://www.ncbi.nlm.nih.gov/pubmed/32364536
http://dx.doi.org/10.1172/JCI133187

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