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Anisotropic ESCRT-III architecture governs helical membrane tube formation

ESCRT-III proteins assemble into ubiquitous membrane-remodeling polymers during many cellular processes. Here we describe the structure of helical membrane tubes that are scaffolded by bundled ESCRT-III filaments. Cryo-ET reveals how the shape of the helical membrane tube arises from the assembly of...

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Detalles Bibliográficos
Autores principales: Moser von Filseck, Joachim, Barberi, Luca, Talledge, Nathaniel, Johnson, Isabel E., Frost, Adam, Lenz, Martin, Roux, Aurélien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260168/
https://www.ncbi.nlm.nih.gov/pubmed/32471995
http://dx.doi.org/10.1038/s41467-020-15327-4