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Structural insight into the electron transfer pathway of a self-sufficient P450 monooxygenase

Cytochrome P450 monooxygenases are versatile heme-thiolate enzymes that catalyze a wide range of reactions. Self-sufficient cytochrome P450 enzymes contain the redox partners in a single polypeptide chain. Here, we present the crystal structure of full-length CYP116B46, a self-sufficient P450. The c...

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Detalles Bibliográficos
Autores principales: Zhang, Lilan, Xie, Zhenzhen, Liu, Ziwei, Zhou, Shuyu, Ma, Lixin, Liu, Weidong, Huang, Jian-Wen, Ko, Tzu-Ping, Li, Xiuqin, Hu, Yuechan, Min, Jian, Yu, Xuejing, Guo, Rey-Ting, Chen, Chun-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260179/
https://www.ncbi.nlm.nih.gov/pubmed/32472090
http://dx.doi.org/10.1038/s41467-020-16500-5