Cargando…

Ovarian BDNF promotes survival, migration, and attachment of tumor precursors originated from p53 mutant fallopian tube epithelial cells

High-grade serous ovarian carcinoma (HGSOC) is the most lethal gynecological malignancy. New evidence supports a hypothesis that HGSOC can originate from fallopian tube epithelium (FTE). It is unclear how genetic alterations and pathophysiological processes drive the progression of FTE tumor precurs...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Min, Chong, Kay Yi, Hartwich, Tobias M. P., Bi, Fangfang, Witham, Allyson K., Patrick, David, Morrisson, Madeline J., Cady, Sarah L., Cerchia, Alexandra P., Kelk, Dawn, Liu, Yifei, Nucci, Jonah, Madarikan, Oluwagbemisola, Ueno, Daiki, Shuch, Brian M., Yang-Hartwich, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260207/
https://www.ncbi.nlm.nih.gov/pubmed/32471985
http://dx.doi.org/10.1038/s41389-020-0243-y