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Ovarian BDNF promotes survival, migration, and attachment of tumor precursors originated from p53 mutant fallopian tube epithelial cells
High-grade serous ovarian carcinoma (HGSOC) is the most lethal gynecological malignancy. New evidence supports a hypothesis that HGSOC can originate from fallopian tube epithelium (FTE). It is unclear how genetic alterations and pathophysiological processes drive the progression of FTE tumor precurs...
Autores principales: | Kang, Min, Chong, Kay Yi, Hartwich, Tobias M. P., Bi, Fangfang, Witham, Allyson K., Patrick, David, Morrisson, Madeline J., Cady, Sarah L., Cerchia, Alexandra P., Kelk, Dawn, Liu, Yifei, Nucci, Jonah, Madarikan, Oluwagbemisola, Ueno, Daiki, Shuch, Brian M., Yang-Hartwich, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260207/ https://www.ncbi.nlm.nih.gov/pubmed/32471985 http://dx.doi.org/10.1038/s41389-020-0243-y |
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