Endoplasmic Reticulum Stress Signalling Induces Casein Kinase 1-Dependent Formation of Cytosolic TDP-43 Inclusions in Motor Neuron-Like Cells

Motor neuron disease (MND) is a progressive neurodegenerative disease with no effective treatment. One of the principal pathological hallmarks is the deposition of TAR DNA binding protein 43 (TDP-43) in cytoplasmic inclusions. TDP-43 aggregation occurs in both familial and sporadic MND; however, the...

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Detalles Bibliográficos
Autores principales: Hicks, David A., Cross, Laura L., Williamson, Ritchie, Rattray, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260270/
https://www.ncbi.nlm.nih.gov/pubmed/31280399
http://dx.doi.org/10.1007/s11064-019-02832-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260270/
https://www.ncbi.nlm.nih.gov/pubmed/31280399
http://dx.doi.org/10.1007/s11064-019-02832-2

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