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What lies beneath: Hydra provides cnidarian perspectives into the evolution of FGFR docking proteins

Across the Bilateria, FGF/FGFR signaling is critical for normal development, and in both Drosophila and vertebrates, docking proteins are required to connect activated FGFRs with downstream pathways. While vertebrates use Frs2 to dock FGFR to the RAS/MAPK or PI3K pathways, the unrelated protein, dow...

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Detalles Bibliográficos
Autores principales: Suryawanshi, Ashwini, Schaefer, Karolin, Holz, Oliver, Apel, David, Lange, Ellen, Hayward, David C., Miller, David J., Hassel, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260276/
https://www.ncbi.nlm.nih.gov/pubmed/32198667
http://dx.doi.org/10.1007/s00427-020-00659-4