Probe-target hybridization depends on spatial uniformity of initial concentration condition across large-format chips

Diverse assays spanning from immunohistochemistry (IHC), to microarrays (protein, DNA), to high-throughput screens rely on probe-target hybridization to detect analytes. These large-format ‘chips’ array numerous hybridization sites across centimeter-scale areas. However, the reactions are prone to i...

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Detalles Bibliográficos
Autores principales: Geldert, Alisha, Huang, Haiyan, Herr, Amy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260366/
https://www.ncbi.nlm.nih.gov/pubmed/32472029
http://dx.doi.org/10.1038/s41598-020-65563-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260366/
https://www.ncbi.nlm.nih.gov/pubmed/32472029
http://dx.doi.org/10.1038/s41598-020-65563-3

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