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Probe-target hybridization depends on spatial uniformity of initial concentration condition across large-format chips
Diverse assays spanning from immunohistochemistry (IHC), to microarrays (protein, DNA), to high-throughput screens rely on probe-target hybridization to detect analytes. These large-format ‘chips’ array numerous hybridization sites across centimeter-scale areas. However, the reactions are prone to i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260366/ https://www.ncbi.nlm.nih.gov/pubmed/32472029 http://dx.doi.org/10.1038/s41598-020-65563-3 |