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lncRNA LEF1-AS1 Promotes Proliferation and Induces Apoptosis of Non-Small-Cell Lung Cancer Cells by Regulating miR-221/PTEN Signaling

INTRODUCTION: LEF1-AS1 is a characterized oncogenic lncRNA in oral cancer. Analysis of TCGA dataset revealed the upregulation of LEF1-AS1 in non-small-cell lung cancer (NSCLC). This study was therefore carried out to investigate the involvement of LEF1-AS1 in NSCLC. METHODS: A total of 62 NSCLC pat...

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Detalles Bibliográficos
Autores principales: Xiang, Chen, Zhang, Yuanli, Zhang, Yajing, Liu, Ci, Hou, Yuehong, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260488/
https://www.ncbi.nlm.nih.gov/pubmed/32547220
http://dx.doi.org/10.2147/CMAR.S246422