Cargando…

Paracrine regulation and improvement of β-cell function by thioredoxin

The failure of insulin-producing β-cells is the underlying cause of hyperglycemia in diabetes mellitus. β-cell decay has been linked to hypoxia, chronic inflammation, and oxidative stress. Thioredoxin (Trx) proteins are major actors in redox signaling and essential for signal transduction and the ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Hanschmann, Eva-Maria, Petry, Sebastian Friedrich, Eitner, Susanne, Maresch, Constanze Christin, Lingwal, Neelam, Lillig, Christopher Horst, Linn, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260591/
https://www.ncbi.nlm.nih.gov/pubmed/32473461
http://dx.doi.org/10.1016/j.redox.2020.101570