Baicalin combats glutamate excitotoxicity via protecting glutamine synthetase from ROS-induced 20S proteasomal degradation

BACKGROUND: Many neuroprotective approaches targeting neurons in animal models fail to provide benefits for the treatment of ischemic stroke in clinic and glial cells have become the targets in some basic studies. Baicalin has neuroprotective effects but the mechanisms related to glial cells are not...

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Detalles Bibliográficos
Autores principales: Song, Xianrui, Gong, Zixuan, Liu, Kaili, Kou, Junping, Liu, Baolin, Liu, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260594/
https://www.ncbi.nlm.nih.gov/pubmed/32473460
http://dx.doi.org/10.1016/j.redox.2020.101559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260594/
https://www.ncbi.nlm.nih.gov/pubmed/32473460
http://dx.doi.org/10.1016/j.redox.2020.101559

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