Cargando…

Metformin protects from oxaliplatin induced peripheral neuropathy in rats

Oxaliplatin is a commonly used drug to treat cancer, extending the rate of disease-free survival by 20% in colorectal cancer. However, oxaliplatin induces a disabling form of neuropathy resulting in more than 60% of patients having to reduce or discontinue oxaliplatin, negatively impacting their cha...

Descripción completa

Detalles Bibliográficos
Autores principales: Martinez, N.W., Sánchez, A., Diaz, P., Broekhuizen, R., Godoy, J., Mondaca, S., Catenaccio, A., Macanas, P., Nervi, B., Calvo, M., Court, F.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260677/
https://www.ncbi.nlm.nih.gov/pubmed/32490289
http://dx.doi.org/10.1016/j.ynpai.2020.100048