Cranial irradiation induces axon initial segment dysfunction and neuronal injury in the prefrontal cortex and impairs hippocampal coupling

BACKGROUND: Radiation therapy for brain tumors commonly induces cognitive dysfunction. The prefrontal cortex (PFC) is crucial for a diverse array of cognitive processes, however, its role in radiation-induced cognitive dysfunction is unknown. We previously found that cranial irradiation impairs neur...

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Detalles Bibliográficos
Autores principales: Zhang, Die, Zhou, Wei, Lam, Thanh Thai, Li, Yan, Duman, Joseph G, Dougherty, Patrick M, Grosshans, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260696/
https://www.ncbi.nlm.nih.gov/pubmed/32642710
http://dx.doi.org/10.1093/noajnl/vdaa058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260696/
https://www.ncbi.nlm.nih.gov/pubmed/32642710
http://dx.doi.org/10.1093/noajnl/vdaa058

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