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Ancestry-specific predisposing germline variants in cancer

BACKGROUND: Distinct prevalence of inherited genetic predisposition may partially explain the difference of cancer risks across ancestries. Ancestry-specific analyses of germline genomes are required to inform cancer genetic risk and prognosis of diverse populations. METHODS: We conducted analyses u...

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Detalles Bibliográficos
Autores principales: Oak, Ninad, Cherniack, Andrew D., Mashl, R. Jay, Hirsch, Fred R., Ding, Li, Beroukhim, Rameen, Gümüş, Zeynep H., Plon, Sharon E., Huang, Kuan-lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260738/
https://www.ncbi.nlm.nih.gov/pubmed/32471518
http://dx.doi.org/10.1186/s13073-020-00744-3