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The corrected gene proximity map for analyzing the 3D genome organization using Hi-C data
BACKGROUND: Genome-wide ligation-based assays such as Hi-C provide us with an unprecedented opportunity to investigate the spatial organization of the genome. Results of a typical Hi-C experiment are often summarized in a chromosomal contact map, a matrix whose elements reflect the co-location frequ...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260828/ https://www.ncbi.nlm.nih.gov/pubmed/32471347 http://dx.doi.org/10.1186/s12859-020-03545-y |