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HMGB1 mediates lipopolysaccharide-induced inflammation via interacting with GPX4 in colon cancer cells

BACKGROUND: Inflammation is one of a main reason for colon cancer progression and poor prognosis. The high-mobility group box-1 (HMGB1) and glutathione peroxidase 4 (GPX4) are responsible for inflammation, but the relationship between HMGB1 and GPX4 remains unknown about inflammation in colon cancer...

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Detalles Bibliográficos
Autores principales: Yang, Yuhan, Yang, Ling, Jiang, Sheng, Yang, Ting, Lan, Jingbin, Lei, Yun, Tan, Hao, Pan, Kejian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260829/
https://www.ncbi.nlm.nih.gov/pubmed/32514250
http://dx.doi.org/10.1186/s12935-020-01289-6