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Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer

BACKGROUND: Studies of cancer mutations have typically focused on identifying cancer driving mutations that confer growth advantage to cancer cells. However, cancer genomes accumulate a large number of passenger somatic mutations resulting from various endogenous and exogenous causes, including norm...

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Detalles Bibliográficos
Autores principales: Kim, Yoo-Ah, Wojtowicz, Damian, Sarto Basso, Rebecca, Sason, Itay, Robinson, Welles, Hochbaum, Dorit S., Leiserson, Mark D. M., Sharan, Roded, Vadin, Fabio, Przytycka, Teresa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260830/
https://www.ncbi.nlm.nih.gov/pubmed/32471470
http://dx.doi.org/10.1186/s13073-020-00745-2