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Endogenous oxidized DNA bases and APE1 regulate the formation of G-quadruplex structures in the genome
Formation of G-quadruplex (G4) DNA structures in key regulatory regions in the genome has emerged as a secondary structure-based epigenetic mechanism for regulating multiple biological processes including transcription, replication, and telomere maintenance. G4 formation (folding), stabilization, an...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260947/ https://www.ncbi.nlm.nih.gov/pubmed/32404420 http://dx.doi.org/10.1073/pnas.1912355117 |