Endogenous oxidized DNA bases and APE1 regulate the formation of G-quadruplex structures in the genome

Formation of G-quadruplex (G4) DNA structures in key regulatory regions in the genome has emerged as a secondary structure-based epigenetic mechanism for regulating multiple biological processes including transcription, replication, and telomere maintenance. G4 formation (folding), stabilization, an...

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Detalles Bibliográficos
Autores principales: Roychoudhury, Shrabasti, Pramanik, Suravi, Harris, Hannah L., Tarpley, Mason, Sarkar, Aniruddha, Spagnol, Gaelle, Sorgen, Paul L., Chowdhury, Dipanjan, Band, Vimla, Klinkebiel, David, Bhakat, Kishor K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260947/
https://www.ncbi.nlm.nih.gov/pubmed/32404420
http://dx.doi.org/10.1073/pnas.1912355117

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