Evolutionary selection of pestivirus variants with altered or no microRNA dependency

Host microRNA (miRNA) dependency is a hallmark of the human pathogen hepatitis C virus (HCV) and was also described for the related pestiviruses, which are important livestock pathogens. The liver-specific miR-122 binds within the HCV 5′ untranslated region (UTR), whereas the broadly expressed let-7...

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Detalles Bibliográficos
Autores principales: Kokkonos, Konstantinos G, Fossat, Nicolas, Nielsen, Louise, Holm, Christina, Hepkema, Wytske M, Bukh, Jens, Scheel, Troels K H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261151/
https://www.ncbi.nlm.nih.gov/pubmed/32374844
http://dx.doi.org/10.1093/nar/gkaa300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261151/
https://www.ncbi.nlm.nih.gov/pubmed/32374844
http://dx.doi.org/10.1093/nar/gkaa300

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